Practice of Medicine

Claims Lesson

Reglan and Tardive Dyskinesia - Black Box Warning May Not Be Enough to Protect Patients

November 26, 2013

The Case

Although the association between Reglan (metoclopramide) and Tardive Dyskinesia (TD) is common knowledge, in February 2009 the FDA mandated a ‘Black Box’ warning of this complication on the drug’s product information material. The “black box” clearly states that drugs containing metoclopramide can cause TD with long term use (three months or longer for people under age 65; a month for …

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